主编《Allergy Bioinformatics》英文专著，相关章节已经被下载16000多次；成果转化产品----预防过敏口腔护理软膏《简敏》达一万多例的应用，效果良好。主持5项国家基金和3个五年计划的国家科技重大专项重大课题任务的研究。10多本SCI杂志常年审稿专家。发表SCI论文50多篇，牵头成果获得广东省科技奖二等奖2项及广州市科技奖一等奖1项，主创授权专利4项，软件著作权1件。

代表性论文

1、Shan Wang, Bowen Liu, Jiahao Huang, Huiru He, Linghui Zhou, Ying He, Jie Yan, Ailin Tao*. Succinate and mtDNA Trigger Atopic March from Atopic Dermatitis to Intestinal Inflammation. J Allergy Clin Immunol. 2023, 151(4):1050-1066.  IF=14.2

2、Xueting Liu, Yanmei Wang, Yueling Zeng, De Wang, Yuhuan Wen, Limin Fan, Ying He, Junyan Zhang, Weimin Sun, Yongping Liu, Ailin Tao*. Microglia–Neuron Interactions Promote Chronic Itch via the NLRP3-IL-1β-GRPR Axis. Allergy. 2023, 78(6):1570-1584. IF=12.4

3、Weimin Sun, Shijie Song, Guangmeng Li, Linghui Zhou, Junmou Xie, Yuhe Guo, Jun Zeng, Junyan Zhang, Linmei Li, Ying He, Jie Yan, Xintao Shuai*, Ailin Tao*. FcRn-targeting and ROS-responsive Fedratinib-incorporated nanoparticles alleviate asthma by inducing eosinophil apoptosis. Allergy. 2023, 78(6):1659-1663. IF=12.4

4、Andong He, Jiaqian Chen, Jieying Guan, Yuye Huang, Huancheng Xie, Honglv Chen, Yuhuan Wen, Qile Chen, Shiyun Xie, Haoyang Li, Changxing Ou, Qingling Zhang*, Ailin Tao*, Jie Yan*. Selective eosinophil necroptosis contributes to airway inflammation and remodeling in asthma. Allergy. 2022, 77(11):3456-3459. IF=12.4

5、Guan J, Yao W, Zhang L, Xie H, Li L, Wen Y, Chen H, Huang Y, Wen J, Ou C, Liang C, Wang J, Zhang Q*, Tao A*, Yan J*. Contribution of Pseudomonas aeruginosa mediated club cell necroptosis to the bias of type 17 inflammation and steroid insensitivity in asthma. Journal of Advanced Research. 2024, S2090-1232(24)00475-2. IF=11.4

6、Wen Y, Chen Q, Wang H, Xie S, Chen H, Yao W, Zhang L, Sun W, Wen J, Yang X, Chung KF, Zhang Q*, Tao A*, Yan J*. Contribution of IL-17C-mediated macrophage polarization to Type 17 inflammation in neutrophilic asthma. Cell Commun Signal. 2024, 22(1):557. IF=8.2

7、Linyi Ma, Ying HE, Huancheng XIE, Jing WANG, Jiaqian Chen, Shijie SONG, Le ZHANG, Linmei LI, He LAI, Yongping LIU, Huifang Chen, Xueyan ZHANG, Xueting Liu, Zehong ZOU, Qingling ZHANG, Jie Yan*, Ailin Tao*. Ferroptotic alveolar epithelial type ll cells drive TH2 and TH17 mixed asthma triggered by birch pollen allergen Bet v 1. Cell Death Discovery. 2024, 10(1):96.  IF=7.0

8、Junyan Zhang , Xiaobin Yang , Guangui Chen , Jintao Hu , Ying He , Jinxiang Ma , Zhaoen Ma , Huifang Chen , Yuyi Huang , Qiurong Wu , Yongping Liu , Lu Yu , Hong Zhang , He Lai , Jianguo Zhang , Jinming Zhai , Minqi Huang , Zehong Zou , Ailin Tao*. Efficacy and Safety of Intratonsillar Immunotherapy for Allergic Rhinitis: A Randomized, Double-blind, Placebo-Controlled Clinical Trial. Ann Allergy Asthma Immunol. 2024, 132(3):346-354. IF= 5.9

9、Jingbo Yang, Guangmeng Li, Jun Yuan, Sibo Jing, Xiangjiang Wang, Fanwen Yang, Yang Liu, Youde Ding, Gang Li, Guoxi Xie, Ailin Tao*, Ming Liu*, Maobin Xie*. A smart silk-based microneedle for cancer stem cell synergistic immunity/hydrogen therapy. Advanced Functional Materials. 2022, 32(14):2206406. IF = 19

10、Xueting Liu, Yanmei Wang, Tianyu Tao, Liping Zeng, De Wang, Yuhuan Wen, Yangyang Li, Zhongqiu Zhao, Ailin Tao*. GRPR/extracellular signal-regulated kinase and NPRA/extracellular signal-regulated kinase signaling pathways play a critical role in spinal transmission of chronic itch. J Invest Dermatol, 2021, 141(4):863-873. IF=6.5

11、Xueting Liu, De Wang, Yuhuan Wen, Liping Zeng, Yangyang Li, Tianyu Tao, Zhongqiu Zhao, Ailin Tao*. Spinal GRPR and NPRA contribute to chronic itch in a murine model of allergic contact dermatitis. J Invest Dermatol, 2020, 140(9):1856-1866.e7. IF =6.5

12、Zhang C, Chen H, He Q, Luo Y, He A, Tao A*, Yan J*, Fibrinogen/AKT/microfilament axis promotes colitis by enhancing vascular permeability. Cell Mol Gastroenterol Hepatol, 2021, 11(3):683-696. IF =7.2

13、Wei Yang, Shuai Liu1, Yunlei Li, Yujie Wang, Yao Deng, Weimin Sun, Hualan Huang, Junmou Xie, Ailin Tao*, Jie Yan*. Pyridoxine induces monocyte-macrophages death as specific treatment of acute myeloid leukemia. Cancer Letters, 2020, 492:96-105. IF= 9.7

14、Chong Zhang, Andong He, Shuai Liu, Qiaoling He, Yiqin Luo, Zhilan He, Yujiao Chen, Ailin Tao*, Jie Yan*. Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells. Cell Death & Disease, 2019, 10:344. IF = 9

代表性项目

1、国家自然科学基金面上项目，TDI结合肺泡巨噬细胞PIEZO1促进Th17分化诱发中性粒细胞难治性哮喘的免疫机制研究，82570054，2026.1-2029.12，49万元

2、国家自然科学基金面上项目，AHR通路协同下的NLRC4炎症小体在低过敏原性免疫毒素PEA残存的超敏反应中的作用机制，81871266，2019.1-2022.12，57万元

3、广州市科技计划重点项目，过敏性疾病发生机制及新型诊治方法的研究201804020042，2018.4-2021.3，200万元

4、国家重大科技专项重大课题任务主持，人体过敏血清库及过敏性评价技术研究，2016ZX08011-005，2016.1-2020.12，331.53万元

5、国家重大科技专项重大课题任务主持，人体过敏血清库及过敏性评价技术研究，2014ZX08011-005，2014.7-2015.12，113万元

6、国家重大科技专项重大课题任务主持，人体过敏血清库及过敏性评价技术研究，2011ZX08011-005，2011.7-2012.12，123万元

7、国家重大科技专项重大课题任务主持，人体过敏血清库及过敏性评价技术研究，2008ZX08011-005，2009.1-2010.12，156万

8、国家自然科学基金面上项目，过敏原家族特征肽调节树突状细胞共刺激分子差异表达的免疫生物信息学解析，81373128，2014.01-2017.12，70万元

代表性成果奖励

1、2024年广东省科学技术进步奖二等奖  过敏性疾病的发生机制及新型防诊治方法

1、2014年广东省科学技术奖二等奖 过敏原性评估及其在食品药品过敏原性改良中的应用

2、2013年广州市科学技术奖一等奖 蛋白质过敏原性的评估与改良技术