全体研究人员 学术带头人
名字:龙琪
职务:
职称:教授
研究方向:慢性气道性疾病
联系方式:longqiking@163.com
研究工作

线粒体代谢与疾病治疗

代表性成果

1、S. Du#; Q. Long#*; Y. Zhou#; J. Fu#; H. Wu; L. Yang; Y.Xie; Y. Ding; M. Zhang; J. Guo; M. Wang; J. Lin; M. Hu; J. Zhang; D. Yao; W. Li; F. Bao; G. Xiang; Y. Wu; Y. Huang; H. Liang; R. Wang; H. Li; B. Chen; C. Li; J. Wang; J. Zhang; D. Qin; J. Sun; Y. Zhu; F. Sun; W. Wang; G. Lu; W. Chan; H. Zhao; C. Liu; X. Liu*; Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkison's disease models, Cell, 2026, 1-13(共一兼通讯)

2、H. Wu#, W. Li#, …, X. Liu*, Q Long*, A new role of Iridium(III) Complexes in regulating pluripotency acquisition via mitochondrial remodulation, Science China Life Sciences, 2026 (末位通讯)

3、Q. Long#, K. Yan#, C. Wang, Y. Wen, F. Qi, H. Wang, P. Shi, X. Liu, W. Y. Chan, Xuemei Lu*, Hui Zhao*, Modification of Maternally Defined H3K4me3 Regulates the Inviability of Interspecific Xenopus Hybrids, Science Advances, 2023. 9(14): p. eadd8343. (IF 16.9)

4、W. Li#, Q. Long#, H. Wu#, Y. Zhou, L. Duan, H. Yuan, Y. Ding, Y. Huang, Y. Wu, J. Huang, D. Liu, B. Chen, J. Zhang, J. Qi, S. Du, L. Li, Y. Liu, Z. Ruan, Z. Liu, Z. Liu, Y. Zhao, J. Lu, J. Wang, W. Y. Chan and X. Liu*, Nuclear Translocation of Mitochondrial TCA Cycle Enzymes Modulates Pluripotency via Histone Acetylation, Nature Communications, 2022. 13(1): 7414. (共一作,IF 17.694,Highlights by editors)

5、Q. Long#, Y. Zhou#, H. Wu#, S. Du, M. Hu, J. Qi, W. Li, J. Guo, Y. Wu, L. Yang, G. Xiang, L. Wang, S. Ye, J. Wen, H. Mao, J. Wang, H. Zhao, W. Y. Chan, J. Liu, Y. Chen, Pi Li and X. Liu*. Phase separation drives the self-assembly of mitochondrial nucleoids for transcription modulation. Nature Structural & Molecular Biology. 2021. 28(11): 900-908. (IF 18.361)

6、Y. Zhou#, Q. Long#, H. Wu, W. Li, J. Qi, Y. Wu, G. Xiang, H. Tang, L. Yang, K. Chen, L. Li, F. Bao, H. Li, Y. Wang. M. Li and X. Liu*. Topology-dependent, bifurcated mitochondrial quality control under starvation. Autophagy. 2020. 16(3): 562-574. (共一作, 封面文章,IF 16.586)

7、X. Su#*, S. Bai#, G. Xie#, Y Shi#, L. Zhao, G. Yang, F. Tian, K. He, L. Wang, X. Li, Q. Long*, Z. Han*,Accurate tumor clonal structures require single-cell analysis. Annals of the New York Academy of Sciences, 2022.1517(1):213-224 (共通讯, IF 6.499)

8、K. Chen#, Q. Long#, T. Wang, D. Zhao, Y. Zhou, J. Qi, Y. Wu, S. Li, C. Chen, X. Zeng, J. Yang, Z. Zhou, W. Qin, X. Liu, Y. Li, Y. Li, X. Huang, D. Qin, J. Chen, G. Pan, H. R. Scholer, G. Xu, X. Liu* and D. Pei*. Gadd45a is a heterochromatin relaxer that enhances iPS cell generation. EMBO Rep. 2016. 17(11): p. 1641-1656. (共一作, IF 10.715)

9、Q. Long#, J. Qi#, W. Li#, Y. Zhou, K. Chen, H. Wu and X. Liu*. Protocol for detecting chromatin dynamics and screening chromatin relaxer by FRAP assay. Star Protocols. 2021. 2(3): 100706. (IF 1.3)

10、Y. Zhou#, Q. Long#, Liu, X*. A new sight: topology-dependent mitophagy. Cell Biology & Toxicology. 2020. 36, 199-204. (共一作,IF 6.029)

11、X. Su#, Q. Long#, J. Bo#, Y. Shi#, L.N. Zhao, Y. Lin, Q. Luo, S. Ghazanfar, C. Zhang, Q. Liu, L. Wang, K. He, J. He, X. Cui, J.Y.H. Yang, Z.G. Han, G. Yang, and J.J. Sha*. Mutational and transcriptomic landscapes of a rare human prostate basal cell carcinoma. Prostate. 2020. 80(6): p. 508-517. (共一作,IF 4.1)

12、Q. Long#, D. Zhao#, W. Fan, L. Yang, Y. Zhou, J. Qi, X. Wang* and X. Liu*. Modeling of Mitochondrial Donut Formation. Biophysical J. 2015. 109(5): p. 892-9. (IF 4.03)

13、Y. Gong#, Q. Long#, H. Xie, T. Zhang and T. Peng*. Cloning and characterization of human Golgi phosphoprotein 2 gene (GOLPH2/GP73/GOLM1) promoter. Biochem Biophys Res Commun. 2012. 421(4):713-720. (共一作,IF=3.6)

14、J. Qi#, Q. Long#, Y. Yuan, Y. Zhou, J. Zhang, Z. Ruan, L. Yang, Y. Wu, G. Xiang, W. Li, H. Wu, S. Du and X. Liu*. Mitochondrial DNA mutation affects the pluripotency of embryonic stem cells with metabolism modulation. Genome Instability & Disease. 2023. 4(1): 12-20. (共一作)

15、Q. Long#, Y. Zhou#, J. Guo, H. Wu and X. Liu. Multi-phase separation in mitochondrial nucleoids and eukaryotic nuclei. Biophysics Reports. 2023. 8: 1-7. (封面,IF=2.7)

16、Chong Li,Hao Wu, Qi Long*. Study the Genomic Stability after Gadd45α Knockout in Embryonics Stem Cells. Acta Scientiarum Naturalium Universitatis Nankaiensis.2022. 0465-7942(2022)01-0007-06;