导师介绍
| 姓名 | 贾楠 | 性别 | 女 |
| 民族 | 汉 | 导师层次 | 硕士生导师 |
| 职称 | 副教授 | 导师类型 | 学术型 |
| 学历 | 博士研究生 | 学位 | 药理学博士 |
| 行政职务 | 无 | 邮箱 | jianan@gzhmu.edu.cn |
| 招生方向 | 免疫学 | ||
副教授，硕士生导师。日本长崎大学药理学博士，曾任日本名古屋大学特任助教，入选广州医科大学“南山学者”。广东省药学会罕见病呼吸学组委员，中华医学会变态反应学分会基础与转化学组（筹）成员。目前为呼吸疾病国家重点实验室哮喘方向核心成员，在《 Nature Protocols 》、《 Journal of Allergy and Clinical Immunology 》、《 Cell 》、《 DNA Repair 》、《 Journal of Medical Genetics 》等国际知名期刊发表多篇学术论文；主持日本国家青年基金 1 项，广东省青年基金 1 项，广州市院校联合基金 1 项，参与多项国家级和省市级科研基金项目。参编奥马珠单抗治疗专家共识。
从事哮喘基因组学以及呼吸系统罕见疾病的分子诊断研究。搭建了哮喘大型样本库和数据库，建立了哮喘基因型 - 表型关联方法学，探讨遗传因素在哮喘中的作用；建立半自动细胞检测平台，可快速检测免疫通路中的 DNA 损伤应答、炎症反应、细胞凋亡等信号。
1、Jia Nan#; Nakazawa Yuka#; Guo Chaowan; Shimada Mayuko; Sethi Mieran; Takahashi Yoshito; Ueda Hiroshi; Nagayama Yuji; Ogi Tomoo*. A rapid, comprehensive system for assaying DNA repair activity and cytotoxic effects of DNA-damaging reagents. Nature Protocols, 2015, 10(1): 12-24. #co-first author. (Q1, IF=17.021)
2、Nan Jia, Chaowan Guo, Yuka Nakazawa, Diana van den Heuvel, Martijn S. Luijsterburg, Tomoo Ogi*. Ubiquitination of DNA damage-stalled RNAPII promotes transcription-coupled repair. DNA Repair, 2021, 103192, https://doi.org/10.1016/j.dnarep.2021.103192. (Q2, IF=4.354)
3、Ruchong Chen#; Ling Sang#; Mei Jiang#; Zhaowei Yang#; Nan Jia#; Wanyi Fu#; Jiaxing Xie; Weijie Guan; Wenhua Liang; Zhengyi Ni; Yu Hu; Lei Liu; Hong Shan; Chunliang Lei; Yixiang Peng; Li Wei; Yong Liu; Yahua Hu; Peng Peng; Jianming Wang; Jiyang Liu; Zhong Chen; Gang Li; Zhijian Zheng; Shaoqin Qiu; Jie Luo; Changjiang Ye; Shaoyong Zhu; Jinping Zheng; Nuofu Zhang; Yimin Li; Jianxing He; Jing Li*; Shiyue Li*; Nanshan Zhong*. Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China. Journal of Allergy and Clinical Immunology, 2020. 146(1) :89-100. #co-first author. (Q1, IF=14.290)
4、Calmels Nadege#; Botta Elena#; Jia Nan#; Fawcett Heather; Nardo Tiziana; Nakazawa Yuka; Lanzafame Manuela; Moriwaki Shinichi; Sugita Katsuo; Kubota Masaya; Obringer Cathy; Spitz Marie Aude; Stefanini Miria; Laugel Vincent; Orioli Donata; Ogi Tomoo; Lehmann Alan Robert*. Functional and clinical relevance of novel mutations in a large cohort of patients with Cockayne syndrome. Journal of Medical Genetics, 2018, 55(5): 329-343. #co-first author. (Q1, IF=5.941)
5、Wenjun Jiang#, Nan Jia#, Chaowan Guo#, Juan Wen, Lingqian Wu, Tomoo Ogi*, Huiwen Zhang*. Predominant cellular mitochondrial dysfunction in the TOP3A gene-caused Bloom syndrome-like disorder. BBA - Molecular Basis of Disease, 2021, 166106, https://doi.org/10.1016/j.bbadis.2021.166106 #co-first author. (Q1, IF=6.633)
6、Yuka Nakazawa; Yuichiro Hara; Yasuyoshi Oka; Okiru Komine; Diana van den Heuvel; Chaowan Guo; Yasukazu Daigaku; Mayu Isono; Yuxi He; Mayuko Shimada; Kana Katoh; Nan Jia; Satoru Hashimoto; Yuko Kotani; Yuka Miyoshi; Miyako Tanaka; Akira Sobue; Norisato Mitsutake; Takayoshi Suganami; Akio Masuda; Kinji Ohno; Shinichiro Nakada; Tomoji Mashimo; Koji Yamanaka; Martijn S. Luijsterburg; Tomoo Ogi*. Ubiquitination of DNA damage-stalled RNAPII promotes transcription-coupled repair. Cell, 2020, 180(6): 1228-1244. (Q1, IF= 66.850)
7、Guo Chaowan; Nakazawa Yuka; Woodbine Lisa; Bjorkman Andrea; Shimada Mayuko; Fawcett Heather; Ohyama Kaname; Li Tao Sheng; Nagayama Yuji; Jia Nan; Mitsutake Norisato; Pan Hammarstrom Qiang; Gennery Andrew R; Lehmann Alan R; Jeggo Penny A; Ogi Tomoo*. XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency. Journal of Allergy and Clinical Immunology, 2015, 136(4): 1007-1017. (Q1, IF=14.290)
8、Qin R, He L, Yang Z, Jia N, Chen R, Xie J, Fu W, Chen H, Lin X, Huang R, Luo T, Liu Y, Yao S, Jiang M, Li J(Corresponding Author). Identification of Parameters Representative of Immune Dysfunction in Patients with Severe and Fatal COVID-19 Infection: a Systematic Review and Meta-analysis. Clinical Review in Allergy & Immunology, 2022 Jan 18:1–33. doi: 10.1007/s12016-021-08908-8. (Q1, IF=10.817)
