代表性科研项目

1、国家自然科学基金青年科学基金项目，82000044，蛋白ALIX通过调控胞外囊泡分泌干预COPD发生发展的作用研究， 2021.01-2023.12，24万，在研，主持；

2、广东省自然科学基金区域联合基金，2020A1515110915，DCN基因修饰的MSC通过外泌体修复COPD损伤的作用及机制研究，2021.01-2023.12，10万，在研，主持；

3、广州市市校联合资助项目基础与应用基础项目，202201020423，miRNA1255通过外泌体调控慢阻肺早期疾病进展的作用和机制研究，2021.11-2023.10，在研，主持；

4、呼吸疾病国家重点实验自主课题基金，SKLRD-Z-202315，CD36通过调控外泌体在早期慢阻肺疾病中的作用和机制研究，2023.01-2025.12，在研，主持；

5、中国博士后科学基金面上资助项目，2019M652860，外泌体参与COPD疾病发生发展的作用及机制研究， 2018.12-2020.04, 8万，结题，主持；

6、中国博士后科学基金专项特别资助项目，2020T130025ZX，探讨新冠病毒与外泌体传播关系及筛选新冠肺炎潜在药物靶点的研究，2020.03-2020.09, 18万，结题，主持；

7、广州市博士后基金，2018206655，外泌体与慢阻肺的关系研究，2018.04-2020.04，结题，主持。

代表性学术论文

1、Binwei Hao#, Ruiting Sun#, Xiaotong Guo, Lili Zhang, Jieda Cui, Yuming Zhou, Wei Hong, Yannan Zhang, Jinxi He, Xiaoming Liu, Bing Li, Pixin Ran*, and Juan Chen*. βNOX4-Derived ROS Promotes Collagen I Deposition in Bronchial Smooth Muscle Cells by Activating Noncanonical p38MAPK/Akt-Mediated TGF- Signaling[J]. Oxid Med Cell Longev, 2021, 2021: 6668971.

2、Ruiting Sun, Yingying Liu, Meng Lu, Qianqian Ding, Pingping Wang, Heng Zhang, Xiaoyu Tian, Dan Meng, Ning Sun, Meng Xiang, Sifeng Chen*. ALIX Increases Protein Content and Beneficial Function of iPSC-derived Exosomes [J]. J Mol Med, 2019. 97: 829-844.

3、Li J#, Feng M#, Ruiting Sun#, Li Z, Hu L, Peng G, Xu X, Wang W, Cui F, Yue W, He J*, Liu J*. Andrographolide ameliorates bleomycin-induced pulmonary fibrosis by suppressing cell proliferation and myofibroblast differentiation of fibroblasts via the TGF-1-mediated Smad-dependent and -independent pathways[J]. Toxicology Letters, 2020, 321: 103-113.

4、Qianqian Ding, Ruiting Sun, Pingping Wang, Heng Zhang, Meng Xiang, Dan Meng, Ning Sun, AlexF Chen, Sifeng Chen*. Protective effects of human induced pluripotent stem cell-derived exosomes on high glucose-induced injury in human endothelial cells. Exp Ther Med, 2018. 15(6): p. 4791-4797.

5、Hua Wang#, Ruiting Sun#, Yang Li, Yuefeng Yang，Fengjun Xiao, Yikun Zhang, Qunwei Zhang, CT Wu*, Lisheng Wang*. HGF Gene Modification in Mesenchymal Stem Cells Reduces Radiation Induced Intestinal Injury by Modulating Immunity [J]. PLoS One. 2015; 10(5): e0124420.

6、Zou, W; Wang, X; Sun, R S ; Hu, J; Ye, D; Bai, G; Liu, S; Hong, W; Guo, M; Ran, P*; PM2.5 In duces Airway Remodeling in Chronic Obstructive Pulmonary Diseases via the Wnt5a/β-Catenin Pathwa y., International Journal of Chronic Obstructive Pulmonary Disease, 2021, 16: 3285-3295

7、Mi Gao; Chunxiao Liang; Wei Hong; Xiaoyuan Yu; Yumin Zhou; Ruiting Sun R; Haiqing Li; Haich ao Huang; Xuhong Gan; Yuan Ze; Jiahuan Zhang; Juan Chen; Qiudi Mo; Luyao Wang; Biting Lin; Bing L i; Pixin Ran*; Biomass-related PM2.5 induces mitochondrial fragmentation and dysfunction in human airway epithelial cells, Environmental Pollution, 2021, 0269(21)

8、Qianqian Ding, Ruiting Sun, Pingping Wang, Heng Zhang, Meng Xiang, Dan Meng, Ning Sun, AlexF Chen, Sifeng Chen*. Protective effects of human induced pluripotent stem cell-derived exosomes on high glucose-induced injury in human endothelial cells. Exp Ther Med, 2018. 15(6): p. 4791-4797.

获奖及个人荣誉

1、广州市高层次人才-青年人才