导师介绍
姓名 | 冯立强 | 性别 | 男 |
民族 | 汉族 | 导师层次 | 博士生导师 |
职称 | 教授 | 导师类型 | 学术型 |
学历 | 博士研究生 | 学位 | 博士 |
行政职务 | 无 | 邮箱 | feng_liqiang@gibh.ac.cn |
招生方向 | 病毒感染与免疫 |
1、新突发病毒性传染病疫苗;
2、基于重组病毒载体、环状RNA、纳米颗粒等的新一代疫苗技术;
3、呼吸道病毒致病机理及干预策略。
科研项目:
1、国家自然科学基金(国际合作项目,82061138006),新型冠状病毒诱导黏膜免疫的机制及预防治疗策略研究,2021.1-2023.12, 主持(在研);
2、广东省自然科学基金(面上项目,2023A1515011468),基于环状RNA的寨卡病毒疫苗研究,10万元,2023.01.01-2025.12.31,主持(在研);
3、国家重大传染病专项(2017ZX10204401),抗H7N9病毒血浆在H7N9感染重症治疗的临床应用,2017.1-2020.12,任务主持(已结题);
4、广州市健康医疗协同创新重大专项(201803040004),病毒感染重症救治的特异性被动免疫应用研究及腺病毒单克隆抗体药物研发,2018.04-2021.03,子课题主持(已结题)
代表性学术论文:
1、Pingchao Li#*, Qian Wang#, Yizi He#, Chenchen Yang#, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng*, Ling Chen*. Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques. Emerging Microbes & Infections. 2023, 12(1): e2136538.
2、Xianmiao Ye#, Xinglong Liu#, Tao Shu, Weiqi Deng, Min Liao, Yali Zheng, Xuehua Zheng, Xiaoyan Zhang, Ting Li, Wenxia Fan, Linbing Qu, Ling Chen, Feng Li*, Liqiang Feng*. A Live-Attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice. Journal of Virology. 2021, 95(14):e0038321.
3、Jinlin Wang#, Tao Shu#, Weiqi Deng, Yali Zheng, Min Liao, Xianmiao Ye, Lujie Han, Ping He, Xuehua Zheng, Ting Li, Ying Feng, Fengyu Hu, Pingchao Li, Caijun Sun, Ling Chen, Feng Li*, Liqiang Feng*. Mucosal priming with a recombinant influenza A virus-vectored vaccine elicits T-cell and antibody responses to HIV-1 in mice. Journal of Virology. 2021, 95(12):e00059-21.
4、Lei Yu#, Xinglong Liu#, Xianmiao Ye#, Wan Su, Xiaoyan Zhang, Weiqi Deng, Jia Luo, Mengrong Xiang, Wenjing Guo, Shengnan Zhang, Wei Xu, Qihong Yan, Qian Wang, Yilan Cui, Caixia Wu, Wenjing Guo, Xuefeng Niu, Fuchun Zhang, Chunliang Lei, Linbing Qu, Ling Chen*, Liqiang Feng*. Monoclonal Antibodies against Zika Virus NS1 Protein Confer Protection via Fcγ Receptor-dependent and -independent Pathways. mBio. 2021, 12(1):e03179-20.
5、Liqiang Feng#, Qian Wang#, Chao Shan#, Chenchen Yang, Ying Feng, Jia Wu, Xiaolin Liu, Yiwu Zhou, Rendi Jiang, Peiyu Hu, Xinglong Liu, Fan Zhang, Pingchao Li, Xuefeng Niu, Yichu Liu, Xuehua Zheng, Jia Luo, Jing Sun, Yingying Gu, Bo Liu, Yongcun Xu, Chufang Li, Weiqi Pan, Jincun Zhao, Changwen Ke, Xinwen Chen, Tao Xu, Nanshan Zhong, Suhua Guan*, Zhiming Yuan*, Ling Chen*. An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques. Nature Communicatons. 2020, 11(1): 4207
6、Ying Feng#, Changhua Yi#, Xinglong Liu#, Linbing Qu, Wan Su, Tao Shu, Xuehua Zheng, Xianmiao Ye, Jia Luo, Mingli Hao, Xikui Sun, Liang Li, Xiaolin Liu, Chenchen Yang, Suhua Guan, Ling Chen and Liqiang Feng*. Human desmoglein-2 and human CD46 mediate HAdV55 infection but human desmoglein-2 plays the major roles. Journal of Virology. 2020, 94(17): e00747-20.
代表专利:
1、代表专利:[1]一种复制缺陷型人55型腺病毒载体及其制备方法和应用;陈凌,冯立强;专利号: 中国201510179459,美国US20180179554A1,欧洲EP3284826B1。(授权);
2、一种重组寨卡病毒减毒株及其制备方法和应用;冯立强,陈凌,叶贤苗;专利号:202110214252.4。(授权);
3、一种节段化的水泡性口炎病毒载体及其制备方法和应用;冯立强,卢俊南;申请号:202211130204.8。(实审);
4、[4]抗丝状病毒单克隆中和抗体及其制备方法和应用;陈凌,冯玉鹏,冯立强,王龙雨;专利号:ZL201910989375.8;申请日期:2019.10.17。(授权)。
获奖及个人荣誉:
1、中国科学院青年创新促进会会员(2015);
2、广州市“珠江科技新星”(2015);