广州医科大学附属第二医院检验科副主任

职称：

副主任技师

研究方向：

重大呼吸系统感染和肺损伤

研究工作：

1、病毒感染免疫研究

2、病毒感染相关诊断方法学研究

3、新型体外检测技术研究

科研项目：

1、基于EB病毒全长蛋白质组芯片技术分析鼻咽癌患者对EB病毒蛋白免疫反应特征研究，广州市市校联合项目，编号：202102010094，研究期限：2021.04-2023.03，20万元

2、基于近红外发光便携式检测技术高灵敏度检测新型冠状病毒核衣壳蛋白的研究，广东省自然科学基金，编号：2021A1515012550, 2021.1.1-2023.12.31，10万元

3、尿液BK病毒特异性抗体特征及其在肾移植受者BK病毒感染疾病诊断和预后评价的多中心临床观察性研究，广州医科大学附属第二医院临床研究项目，2024.1.1-2026.12.31，30万元

代表性学术论文：

1、Ji T#, Xu X#, Wang X, et al. Point of care upconversion nanoparticles-based lateral flow assay quantifying myoglobin in clinical human blood samples [J]. Sensors and Actuators B: Chemical. 2019, 282: 309-316.

2、Ji T#, Xu X#, Wang X#, et al. Background-Free Chromatographic Detection of Sepsis Biomarker in Clinical Human Serum through Near-Infrared to Near-Infrared Upconversion Immunolabeling [J]. ACS nano 2020, 14(12): 16864-16874.

3、Ji T#*., Liu Y#, Li Y, et al. Molecular typing and genomic characteristic of human adenoviruses in Datong, Northern China [J]. Journal of medical virology 2020, 92(12): 1-8.

4、Ji T#*., Li L#, Li W#, et al.Emergence and characterization of a putative novel human adenovirus recombinant HAdV-C104 causing pneumonia in Southern China [J]. Virus evolution 2021, 7(1): veab018

5、Lai C#, Liu X#, Yan Q#, Lv H#, Zhou L#, Hu L, Cai Y, Wang G, Chen Y, Chai R, Liu Z, Xu Y, Huang W, Xiao F, Hu L, Li Y, Huang J, Zhou Q, Li L, Peng T, Zhang H, Zhang Z*., Chen L*., Chen C*., Ji T*. Low Innate Immunity and Lagged Adaptive Immune Response in the Re-Tested Viral RNA Positivity of a COVID-19 Patient [J]. Frontiers in Immunology 2021, 12: 664619.

6、Kong W#, Zhong Q#, Chen M#, Yu P#, Xu R#, Zhang L, Lai C, Deng M, Zhou Q, Xiong S, Liang Y, Wan L, Lin M, Wang M, Mai W, Chen L, Lei Y, Qin N, Zhu J, Ruan J, Huang Q, Kang A*, Wang J*, Li W*, Ji T*. Ad5-nCoV booster and Omicron variant breakthrough infection following two doses of inactivated vaccine elicit comparable antibody levels against Omicron variants [J]. Journal of medical virology. 2023, 95(1):e28163

7、Zhang L#, Yang JQ#, Lai CC#, Wan L#, Xiong SL#, Kong WY#, Liu ZJ, Yu P, Chen MX, Mai WK, Khan SA, Deng M, Chen L, Lei Y, Zhou Q, Yu N*, Li PC*, Chen CZ*, Ji TX*. Immunity against Delta and Omicron variants elicited by homologous inactivated vaccine booster in kidney transplant recipients [J]. Frontiers in immunology. 2023, 13:1042784

8、Yu P#, Liu ZJ#, Zhu ZQ#, Yang JQ#, Deng M#, Chen MX, Lai CC, Kong WY, Xiong SL, Wan L, Mai WK, Chen L, Lei Y, Khan SA, Ruan JF, Kang A, Guo XG, Zhou Q, Li WR, Chen Z*, Liang YM*, Li PC*, Zhang L*, Ji T*. Omicron variants breakthrough infection elicited higher specific memory immunity than third dose booster in healthy vaccinees[J]. Virologica Sinica. 2023, 2:S1995-820X(22)00214-0

9、Zhu A#, Wei P#, Man M#, Liu X#, Ji T(共同第一作者)#, Chen J, Chen C, Huo J, Wang Y, Zhao J. Antigenic characterization of SARS-CoV-2 Omicron subvariants XBB.1.5, BQ.1, BQ.1.1, BF.7 and BA.2.75.2 [J]. Signal Transduction and Targeted Therapy 2023, 8(1): 125

10、Song Q#, Zhao L#, Mai W#, Xia D#, Ding W, Zhou X, Deng M, Lei Y, Chen L, Li Y, Mai X, Zhang L, Chen Z, Qin Y, Ren R, Wei W*, Ji T*. Handheld NIR-to-NIR Platform for on-site evaluating protective neutralizing antibody against SARS-CoV-2 ancestral strain and Omicron variant after vaccination or infection, Biosensors & bioelectronics 2023, 234:115353.

11、Tang Z#, Yu P#, Guo Q#, Chen M#, Lei Y#, Zhou L, Mai W, Chen L, Deng M, Kong W, Niu C,Xiong X,Li W,Chen C, Lai C*, Wang Q*, Li B*, Ji T*. Clinical characteristics and Host immunity responses of SARS-CoV-2 Omicron variant BA.2 with deletion of ORF7a, ORF7b and ORF8. Virology Journal, 2023, (20):106

12、Zhao L#, Song Q#, Deng M, Mai W, Lei Y, Chen L, Kong W, Zhang L, Li Y, Ye H, Zhang L, Qin Y, Hu Y, Zhang T, Ji T* (共同通讯作者), Wei W*. Engineering Highly Efficient NIR-II FRET Platform for Background-Free Homogeneous Detection of SARS-CoV-2 Neutralizing Antibodies in Whole Blood. Chemical engineering journal, 2023, (468):143616

联系方式：

Email: jitianxing7021@163.com