职称：

研究员

研究方向：

重大呼吸系统感染和肺损伤

研究工作：

病毒与宿主互作机制及其药物与疫苗研发

科研项目：

1、国家自然科学基金委员会, 青年科学基金项目, 82102385, CBX4形成液相分离小体并SUMO化EZH2促进HIV-1潜伏感染的机制研究, 2022-01-01 至 2024-12-31, 30万元, 在研, 主持

2、中国博士后科学基金会, 博士后创新人才支持计划, BX20190398, HIV-1潜伏感染的表观遗传学和转录调控机制研究, 2019-07 至 2021-05, 60万元, 结题, 主持

代表性学术论文：

1、Ma, Xiancai#; Zou, Fan#; Yu, Fei#; Li, Rong#; Yuan, Yaochang#; Zhang, Yiwen#; Zhang, Xiantao; Deng, Jieyi; Chen, Tao; Song, Zheng; Qiao, Yidan; Zhan, Yikang; Liu, Jun; Zhang, Junsong; Zhang, Xu; Peng, Zhilin; Li, Yuzhuang; Lin, Yingtong; Liang, Liting; Wang, Guanwen; Chen, Yingshi; Chen, Qier; Pan, Ting; He, Xin; Zhang, Hui*; Nanoparticle vaccines based on the receptor binding domain (RBD) and heptad repeat (HR) of SARS-CoV-2 elicit robust protective immune responses, Immunity, 2020, 53(6): 1315-1330.e9

2、Ma, Xiancai#; Chen, Tao; Peng, Zhilin; Wang, Ziwen; Liu, Jun; Yang, Tao; Wu, Liyang; Liu, Guangyan; Zhou, Mo; Tong, Muye; Guan, Yuanjun; Zhang, Xu; Lin, Yingtong; Tang, Xiaoping; Li, Linghua; Tang, Zhonghui; Pan, Ting; Zhang, Hui*; Histone chaperone CAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies, The EMBO Journal, 2021, 19(2)

3、Wu, Liyang#; Pan, Ting#; Zhou, Mo; Chen, Tao; Wu, Shiyu; Lv, Xi; Liu, Jun; Yu, Fei; Guan, Yuanjun; Liu, Bingfeng; Zhang, Wanying; Deng, Xiaohui; Chen, Qianyu; Liang, Anqi; Lin, Yingtong; Wang, Lilin; Tang, Xiaoping; Cai, Weiping; Li, Linghua; He, Xin; Zhang, Hui*; Ma, Xiancai*; CBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2, EMBO Reports, 2022, 23(7)

4、Ma, Xiancai#; Yang, Tao; Luo, Yuewen; Wu, Liyang; Jiang, Yawen; Song, Zheng; Pan, Ting; Liu, Bingfeng; Liu, Guangyan; Liu, Jun; Yu, Fei; He, Zhangping; Zhang, Wanying; Yang, Jinyu; Liang, Liting; Guan, Yuanjun; Zhang, Xu; Li, Linghua; Cai, Weiping; Tang, Xiaoping; Gao, Song; Deng, Kai; Zhang, Hui*; TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb, eLife, 2019, 8

5、Yu, Fei#; Pan, Ting#; Huang, Feng#; Ying, Ruosu; Liu, Jun; Fan, Huimin; Zhang, Junsong; Liu, Weiwei; Lin, Yingtong; Yuan, Yaochang; Yang, Tao; Li, Rong; Zhang, Xu; Lv, Xi; Chen, Qianyu; Liang, Anqi; Zou, Fan; Liu, Bingfeng; Hu, Fengyu; Tang, Xiaoping; Li, Linghua; Deng, Kai; He, Xin; Zhang, Hui; Zhang, Yiwen; Ma, Xiancai*; Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 by Suppressing the Proteolytic Activity of Cathepsin L, Frontiers in Microbiology, 2022, 13

获奖及个人荣誉：

1、马显才(2/4); RNA腺苷脱氨酶1通过促进microRNA-122表达抑制HBV的复制, 沈阳市科学技术协会, 沈阳市自然科学学术成果奖, 其他, 2020(刘光焱; 马显才; 王喆; 若江亨祥)

2、马显才(3/4); 核苷脱氨酶家族抗乙肝病毒的研究, 辽宁省医学会, 辽宁省医学科技奖, 其他, 2019(刘光焱; 王喆; 马显才; 王思桐)

联系方式：

Email: ma_xiancai@gzlab.ac.cn