职称：

研究员

研究方向：

重大呼吸系统感染和肺损伤

研究工作：

研究聚焦于人工智能、组学大数据整合分析、单细胞基因组学和群体遗传学的新算法和工具的研发，并使用这些新技术和方法研究基因组序列的调控规则和呼吸系统相关疾病中的重要生物学问题。

代表性学术论文：

1、Yu F, Cato LD, Weng C, Liggett LA, Jeon S, Xu K, Chiang CWK, Wiemels JL, Weissman JS, de Smith AJ, Sankaran VG*. Variant to function mapping at single-cell resolution through network propagation. Nature Biotechnology. 2022. (Journal Impact Factor: 68.16) Highlighted by Nature Genetics, NYSCF, Broad Institute, BioArt, etc.

2、Voit R#, Tao L#, Yu F#, Cato L, Cohen B, Liao X, Claudia F, Nandakumar S, Wahlster L, Kristian T, Regev A*, Sankaran VG*. A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. Nature Immunology. 2022. (Journal Impact Factor: 31.25) Highlighted by Boston Children’s Hosipital, BioArt, etc.

3、Yu F#, Li K#, Li S#, Liu J, Zhang Y, Zhou M, Zhao H, Chen H, Wu N, Liu Z*, Su J*. CFEA: a cell-free epigenome atlas in human diseases. Nucleic Acids Res. 2020. (Journal Impact Factor: 19.16)

4、Yu F#, Quan F#, Xu J#, Zhang Y#, Xie Y, Zhang J, Lan Y, Yuan H, Zhang H, Cheng S*, Xiao Y*, Li X*. Breast cancer prognosis signature: linking risk stratification to disease subtypes. Brief Bioinform. 2019. (Journal Impact Factor: 11.62)

5、Yu F, Sankaran VG, Yuan GC*. CUT&RUNTools 2.0: A pipeline for single-cell and bulk-level CUT&RUN and CUT&Tag data analysis. Bioinformatics. 2021. (Journal Impact Factor: 6.94)

6、Zhang Y#, Zhang Y#, Hu J#, Zhang J, Guo F, Zhou M, Zhang G*, Yu F*, Su J*. scTPA: a web tool for single-cell transcriptome analysis of pathway activation signatures. Bioinformatics. 2020. (Journal Impact Factor: 6.94)

7、Yu F#, Zhang G#, Shi A#, Hu J, Li F, Zhang X, Zhang Y, Huang J, Xiao Y*, Li X*, Cheng S*. LnChrom: a resource of experimentally validated lncRNA-chromatin interactions in human and mouse. Database (Oxford). 2018. (Journal Impact Factor: 3.45)

联系方式：

Email: yu_fulong@gzlab.ac.cn