长期从事PM2.5与慢性呼吸系统疾病、肺再生修复、表观遗传学研究。

1、国家自然科学基金面上项目，32270790，《PM2.5介导P2RY4-YAP通路调控线粒体分裂在COPD肺泡上皮细胞分化异常的机制研究》，53万元，2023/01-2026/12，主持；

2、国家自然科学基金委员会重点项目，42130611，《大气环境条件对病毒传播的影响机制》，289万元，2022/01-2026/12，合作单位负责人；

3、广东省自然科学基金面上项目，2021A1515010913，《METTL16介导m6A修饰在PM2.5诱发COPD肺微血管损伤中的作用及机制研究》，2021/01-2023/12，主持；

4、国家自然科学基金专项项目，42041002，《病毒气溶胶感染活性在大气传播过程中的演变规律》，2020/04-2020/12，合作单位负责人；

5、广东省自然科学基金自由申请项目，2018A0303130281，《PM2.5通过miR-21靶向网络诱发COPD探究》，2018/05-2021/04，主持

近年科研文章
1、Huijuan Zhu, Yiling Zhao, Yingchao Qin, Wenfeng Huang, Jiarui Weng, Zihan Liu, Jiahong Kuang, Zibei Feng, Zhilian Ye, Peiji Zheng, Xiaolan Guo, Fei Cui*, Bingjie Chen*, Pixin Ran*, Jianwei Dai*, Targeting Elastin-Derived Peptides Reverses Alveolar Epithelial Dysfunction in Chronic Obstructive Pulmonary Disease. MedComm, 2026 Jul 25;7(8):e70889

2、Haibo Su#, Baoying Zhang, Qiudi Deng, Jiaxin Huang, Jinyu Feng, Yuan Fu, Yuejun Huang, Weikun Deng, YingJun Su, Huisheng Liu, Ning-Yi Shao, Zhenhui Zhang*, Jianwei Dai*, Trained Immunity Exacerbates Inflammatory Arthritis Progression via Promoting Synovial Fibroblast Ferroptotic Resistance. Advanced Science, 2025 Nov 19;12(46):e04245.

3、Xiaolan Guo, Siqi Yang, Huijuan Zhu, Fengdong Liu, Kai Li, Guojun Li, Yuyin Lin, Hongjiao Yu, Wenxi Qiu, Hao Xu, Qiao Liu, Xinran Xie, Yaowei Sun, Peiji Zheng, Bingjie Chen, Zihan Liu, Xiaopeng Yuan, Shuyi Peng, Xinhui Bi, Jingwen Yang, Ning yi Shao, Jianwei Dai. Involvement of M2 macrophages polarization in PM2.5-induced COPD by upregulating MMP12 via IL4/STAT6 pathway. Ecotoxicology and Environmental Safety, 2024, 283 116793-116793.

4、Shuyi Peng#, Guojie Li#, Yuyin Lin#, Xiaolan Guo, Hao Xu, Wenxi Qiu, Huijuan Zhu, Jiaying Zheng, Wei Sun, Xiaodong Hu, Guohua Zhang, Bing Li, Janak L Pathak*, Xinhui Bi* and Jianwei Dai*. Stability of SARS-CoV-2 in cold-chain transportation environments and the efficacy of disinfection measures. Frontiers in Cellular and Infection Microbiology, 2023, 13(1170505) doi.org/10.3389/fcimb.2023.1170505.

5、Hongjiao Yu#, Yingnan Lin#, Yue Zhong#, Xiaolan Guo, Yuyin Lin, Siqi Yang, Jinglin Liu, Xinran Xie, Yaowei Sun, Dong Wang, Bing Li, Pixin Ran*, Jianwei Dai*. Impaired AT2 to AT1 Cell Transition in PM2.5-induced mouse model of chronic obstructive pulmonary disease. Respiratory Research, 2022 Mar 25;23(1):70

6、Xiaolan Guo#, Yuyin Lin#, Yingnan Lin, Yue Zhong, Hongjiao Yu, Yibin Huang, Jingwen Yang, Y ing Cai, FengDong Liu, Yuanyuan Li, Qian-Qian Zhang, Jianwei Dai*. PM2.5 induces pulmonary microv ascular injury in COPD via METTL16-mediated m6A modification, Environmental Pollution, 2022, 11915.

7. Junchen Li#, Lixun Huang#, Zinan He, Minggui Chen, Yi Ding, Yuying Yao, Youfa Duan, Zixuan Li, Cuiling Qi, Lingyun Zheng, Jiangchao Li, Rongxin Zhang, Xiaoming Li, Jianwei Dai*, Lijing Wang*, Qian Qian Zhang*. Andrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway, Frontiers in Cell and Developmental Biology. 2021, 9(643525) doi:10.3389/FCELL.2021.643525.

近年专利

1、戴建威，陈萍，钟安城，汪婉煜，郭晓兰,粟海波，一株铜绿假单胞菌噬菌体vB-PaeS-GZMU-S12及其应用，发明专利，专利号/申请号：CN202610748626.3，申请公布号：CN122278783A，申请公开/公告日：2026-06-26

2、戴建威，章倩倩，张智勇，粟海波，付源，刘乔，张一心，张桂洲，韦明光，李伯屹，一种携带miR-125a-5p外泌体在急性肺损伤中的应用，发明专利，中国，专利号/申请号：CN202512022391.8，申请公开/公告日：2026.02.10.

3、戴建威，陈冰洁，朱慧娟，杨思琪，郭晓兰，赵祎玲，黄文峰，一种荧光与条形码谱系追踪的肺泡类器官及其构建方法和应用，中国，专利号/申请号：ZL202411796717.1，申请日期2024.12.09，授权公告号：CN119592498B，授权日期：2026.07.31.

4、黄佩瑜，徐浩，冉丕鑫，周玉民，戴建威，王忠芳，一种动物烟雾暴露设备，实用新型专利，中国，申请/专利号：CN202320311097.2，申请日期：2023.02.24，公开/公告号：CN219700199U，公开/公告日：2023.09.19.