全体研究人员 学术带头人

戴建威

职务:

广州医科大学发展规划处副处长、生科院副院长

职称:

教授

研究方向:

慢性气道疾病

研究工作:

1、肺泡再生修复异常参与慢阻肺机制研究;

2、肺微血管损伤参与慢阻肺机制研究;

3、间充质干细胞来源外泌体对肺损伤修复疗效及机制探究;

4、环境对新冠病毒传播的影响;

科研项目:

1、国家自然科学基金面上项目,32270790,《PM2.5介导P2RY4-YAP通路调控线粒体分裂在COPD肺泡上皮细胞分化异常的机制研究》,53万元,2023/01-2026/12,主持;

2、国家自然科学基金委员会重点项目,42130611,《大气环境条件对病毒传播的影响机制》,289万元,2022/01-2026/12,合作单位负责人;

3、广东省自然科学基金面上项目,2021A1515010913,《METTL16介导m6A修饰在PM2.5诱发COPD肺微血管损伤中的作用及机制研究》,2021/01-2023/12,主持;

4、国家自然科学基金专项项目,42041002,《病毒气溶胶感染活性在大气传播过程中的演变规律》,2020/04-2020/12,合作单位负责人;

5、广东省自然科学基金自由申请项目,2018A0303130281,《PM2.5通过miR-21靶向网络诱发COPD探究》,2018/05-2021/04,主持

代表性学术论文:

1、Shuyi Peng#, Guojie Li#, Yuyin Lin#, Xiaolan Guo, Hao Xu, Wenxi Qiu, Huijuan Zhu, Jiaying Zheng, Wei Sun, Xiaodong Hu, Guohua Zhang, Bing Li, Janak L Pathak*, Xinhui Bi* and Jianwei Dai*. Stability of SARS-CoV-2 in cold-chain transportation environments and the efficacy of disinfection measures. Frontiers in Cellular and Infection Microbiology, 2023.

2、Hongjiao Yu#, Yingnan Lin#, Yue Zhong#, Xiaolan Guo, Yuyin Lin, Siqi Yang, Jinglin Liu, Xinran Xie, Yaowei Sun, Dong Wang, Bing Li, Pixin Ran*, Jianwei Dai*. Impaired AT2 to AT1 Cell Transition in PM2.5-induced mouse model of chronic obstructive pulmonary disease. Respiratory Research, 2022.

3、Xiaolan Guo#, Yuyin Lin#, Yingnan Lin, Yue Zhong, Hongjiao Yu, Yibin Huang, Jingwen Yang, Y ing Cai, FengDong Liu, Yuanyuan Li, Qian-Qian Zhang, Jianwei Dai*. PM2.5 induces pulmonary microv ascular injury in COPD via METTL16-mediated m6A modification, Environmental Pollution, 2022.

4、Shiwen Wang#, Yuyin Lin#, Yue Zhong#, Maozhou Zhao, Wei Yao, Xiaohui Ren, Qin Wang, Xiaolan Guo*, QianQian Zhang*, Jianwei Dai*. The long noncoding RNA HCG18 participates in PM2.5-mediated vascular endothelial barrier dysfunction. Aging. 2020.

5、Jianwei Dai*, Wensheng Chen, Yuyin Lin, Shiwen Wang, Xiaolan Guo, Qian-Qian Zhang. Exposure to Concentrated Ambient Fine Particulate Matter Induces Vascular Endothelial Dysfunction via miR-21. International Journal of Biological Sciences. International Journal of Biological Sciences, 2017.

6、Jianwei Dai, Yuyin Lin, Youfa Duan, Zixuan Li, Dalei Zhou, Wensheng Chen, Lijing Wang and Qian-Qian Zhang. Andrographolide inhibits angiogenesis by inhibiting the miR-21-5p/TIMP3 signaling pathway. International Journal of Biological Sciences, 2017.

联系方式:

Email: daijw@gzhmu.edu.cn