全体研究人员 学组组长

何建行

职务:

广州呼吸健康研究院院长、广州实验室临床基地/国家呼吸医学中心主任

职称:

教授

研究方向:

肺癌

研究工作:

长期从事肺癌外科与移植领域医教研及转化工作:

1、胸外科肺部肿瘤的早期诊断与治疗

2、晚期慢性阻塞性肺部疾病的治疗

科研项目:

1、国家重点研发计划——肺部等软组织穿刺手术机器人产品研发与示范应用

代表性学术论文:

1、He J,Su C, Liang W, Xu S, Wu L, Fu X, et al. Icotinib versus chemotherapy as adjuvant treatment for stage II-IIIA EGFR-mutant non-small-cell lung cancer (EVIDENCE): a randomised, open-label, phase 3 trial. Lancet Respir Med. 2021;(21)00134-X

2、Liang W, Liang H, Ou L, Chen B, Chen A, Li C, Li Y, Guan W, Sang L, Lu J, Xu Y, Chen G, Guo H, Guo J, Chen Z, Zhao Y, Li S, Zhang N, Zhong N, He J; China Medical Treatment Expert Group for COVID-19. Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19. JAMA Intern Med.2020;180(8):1081-1089.

3、Zhao Y, Liu J, Cai X, Pan Z, Liu J, Yin W, Chen H, Xie Z, Liang H, Wang W, Guo Z, Zhao S, Liang W, He J. Efficacy and safety of first line treatments for patients with advanced epidermal growth factor receptor mutated, non-small cell lung cancer: systematic review and network meta-analysis.BMJ.2019;367:l5460

4、He J, Baxter SL, Xu J, Xu J, Zhou X, Zhang K. The practical implementation of artificial intelligence technologies in medicine.Nat Med.2019 Jan;25(1):30-36.

5、Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J. Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.Lancet Digit Health.2023;5(9):e560-e570

6、He J, Wang B, Tao J, Liu Q, Peng M, Xiong S, Li J, Cheng B, Li C, Jiang S, Qiu X, Yang Y, Ye Z, Zeng F, Zhang J, Liu D, Li W, Chen Z, Zeng Q, Fan JB, Liang W. Accurate classification of pulmonary nodules by a combined model of clinical, imaging, and cell-free DNA methylation biomarkers: a model development and external validation study.Lancet Digit Health.2023;5(10):e647-e656.

7、Huang Q, Liu L, Xiao D, Huang Z, Wang W, Zhai K, Fang X, Kim J, Liu J, Liang W, He J, Bao S. CD44+ lung cancer stem cell-derived pericyte-like cells cause brain metastases through GPR124-enhanced trans-endothelial migration.Cancer Cell.2023;41(9):1621-1636.e8.

获奖及个人荣誉:

1、国家科学技术进步奖二等奖

2、国家科学技术进步奖创新团队奖

3、全国创新争先奖状

4、全国创新争先奖牌

5、广东省科技进步奖特等奖

6、全国五一劳动奖章

7、国务院政府特殊津贴专家

8、卫生部突出贡献中青年专家

9、广东特支计划杰出人才

联系方式:

Email: Hejx@vip.163.com