All The Researchers

王新华

职务:

广州医科大学校长

职称:

教授

研究方向:

中西医结合临床、中医药抗病毒感染

研究工作:

以中医药临床经验医学为基础和线索,运用现代植物化学技术、药理学技术等, 二次开发或研发新型的抗呼吸道病毒感染中药,并结合循证医学理念,开展中药的临床研究,凸显中医药特色。

科研项目:

1、国家自然科学基金-云南联合基金(U1502226):滇药臭灵丹靶向流感病毒和宿主免疫调节的新型活性成分药效机制及构效关系研究

2、广东省普通高校工程技术研究(开发)中心(GCZX-A1408):中药抗病毒评价及新药研发中心

3、广州市教育系统创新学术团队(13C07):呼吸道病毒性疾病的创新中药研究

代表性学术论文:

1、Wang Y, Li J, Yan W, Chen Q, Jiang Z, Zhang R , Pan X, Wang X*.An active component containing pterodontic acid and pterodondiol isolated from Laggera pterodonta inhibited influenza A virus infection through TLR7/MyD88/TRAF6/ NF-КB signaling pathway. Molecular Medicine Reports2018; 18(1):523-531

2、Yan W, Zheng C, He J, Zhang W, Huang XA, Li X, Wang Y*, Wang X*.Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Int J Mol Med 2018; 42(5):2776-2792.

3、Wang B, Dai Z, Yang XW, Liu YP, Khan A, Yang ZF, Huang WY, Wang XH*, Zhao XD*, Luo XD*. Novel nor-monoterpenoid indole alkaloids inhibiting glioma stem cells from fruits of Alstoniascholaris. Phytomedicine 2018; 48:170-178.

4、Wang B, Yang ZF, Zhao YL, Liu YP, Deng J, Huang WY, Li XN, Wang XH*, Luo XD*.Anti-Inflammatory Isoquinoline with Bis- seco-aporphine Skeleton from Dactylicapnosscandens.Org Lett 2018; 20(6):1647-1650.

5、Ding CF, Ma HX, Yang J, Qin XJ, Njateng GSS, Yu HF, Wei X, Liu YP, Huang WY, Yang ZF, Wang XH*, Luo XD*.Antibacterial Indole Alkaloids with Complex Heterocycles from Voacanga africana. Org Lett 2018; 20(9):2702-2706.

6、Zhao YL, Yang ZF, Shang JH, Huang WY, Wang B, Wei X, Khan A, Yuan ZW, Liu YP, Wang YF, Wang XH*, Luo XD*.Effects of indole alkaloids from leaf of Alstonia scholaris on post-infectious cough in mice. J Ethnopharmacol 2018; 218:69-75.

7、Wang Y, Zhou B, Lu J, Chen Q, Ti H, Huang W, Li J, Yang Z, Jiang Z, Wang X*.Inhibition of influenza virus via a sesquiterpene fraction isolated from Laggera pterodonta by targeting the NF-κB and p38 pathways. BMC Complementary and Alternative Medicine2017; 17(1):25.

8、Wang Y, Yan W, Chen Q, Huang W, Yang Z*, Li X*, Wang X*. Inhibition viral RNP and anti-inflammatory activity of coumarins against influenza virus. Biomedicine & Pharmacotherapy2017; 87:583-588.

9、Guan W , Li J, Chen Q, Jiang Z, Zhang R, Wang X* Yang Z*, Pan X*. Pterodontic Acid Isolated from Laggera pterodonta Inhibits Viral Replication andInflammation Induced by Influenza A Virus. Molecules2017; 22(10). pii: E1738.

获奖及个人荣誉:

1、国务院政府特殊津贴专家

2、“抗药性恶性疟防治药青蒿素复方的研发与应用”获国家科技进步二等奖,2005;(排名第四)

联系方式:

Email: xinhuaw@gzhmu.edu.cn